Epinephrine Bitartrate

Products in Health Canada’s databases that list Epinephrine Bitartrate as a medicinal or active ingredient, under this spelling. The same substance can be listed under another name (a salt, a common name), which has its own page.

Drug products: 26; 10 authorized now
Natural health products: 0; 0 active licences
Notices of Compliance: 40
Products in all: 26

Drug products

Authorized products first.

Name	DIN	Status	Holder	Status since
ARTICAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE INJECTION (0.009 MG)	02339536	Marketed	Pierrel S.P.A.	May 2023
ARTICAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE INJECTION (0.018 MG)	02339544	Marketed	Pierrel S.P.A.	May 2023
MARCAINE (0.0091 MG)	02474247	Marketed	Septodont	Apr 2019
MARCAINE E (0.182 MG)	02241915	Marketed	Pfizer Canada Ulc	Sep 2017
MARCAINE E (0.182 MG)	02241916	Marketed	Pfizer Canada Ulc	Sep 2017
ORABLOC 1:100,000 (0.018 MG)	02361914	Marketed	Pierrel S.P.A.	May 2023
ORABLOC 1:200,000 (0.009 MG)	02361906	Marketed	Pierrel S.P.A.	May 2023
TRI-SOLFEN (0.025 MG)	02528223	Marketed	Medical Ethics Pty Ltd	Sep 2026
BUPIVACAINE HCL 0.5% AND EPINEPHRINE 1:200,000 INJECTION (0.0091 MG)	02381850	Dormant	Novocol Pharmaceutical of Canada, Inc.	Jul 2026
VIVACAINE (0.0091 MG)	02305135	Dormant	Septodont	Jul 2024
E-PILO 1 OPHTHALMIC SOLUTION (10 MG)	02133180	Cancelled Post Market	Ciba Vision Canada Inc	Jan 1999
E-PILO 2 OPHTHALMIC SOLUTION (10 MG)	02133199	Cancelled Post Market	Ciba Vision Canada Inc	May 1999
E-PILO 4 OPHTHALMIC SOLUTION (10 MG)	02133202	Cancelled Post Market	Ciba Vision Canada Inc	Jul 1999
E-PILO 6 OPHTHALMIC SOLUTION (10 MG)	02133210	Cancelled Post Market	Ciba Vision Canada Inc	May 1999
E-PILO-1 OPH SOLN (10 MG)	00760021	Cancelled Post Market	Iolab Pharmaceuticals	Sep 1996
E-PILO-2 OPH SOLN (10 MG)	00759996	Cancelled Post Market	Iolab Pharmaceuticals	Jul 1997
E-PILO-4 OPH SOLN (10 MG)	00760013	Cancelled Post Market	Iolab Pharmaceuticals	Sep 1996
E-PILO-6 OPH SOLN (10 MG)	00760005	Cancelled Post Market	Iolab Pharmaceuticals	Jul 1997
LIDOCAINE 2% AND EPINEPHRINE 1:100 000 (0.0204 MG)	02139006	Cancelled Post Market	Kodak Canada Inc.	Jul 2008
LIDOCAINE 2% AND EPINEPHRINE 1:100,000 (0.01 MG)	02270978	Cancelled Post Market	Carestream Health Canada Company	Sep 2018
LIDOCAINE 2% AND EPINEPHRINE 1:50 000 (.0407 MG)	02138999	Cancelled Post Market	Kodak Canada Inc.	Jul 2008
LIDOCAINE 2% AND EPINEPHRINE 1:50,000 (0.02 MG)	02271001	Cancelled Post Market	Carestream Health Canada Company	Sep 2018
MARCAINE (0.0091 MG)	02311887	Cancelled Post Market	Carestream Health Canada Company	Sep 2018
MARCAINE 0.5% AND EPINEPHRINE 1:200,000 LIQ (9.1 MCG)	01990616	Cancelled Post Market	Kodak Canada Inc.	Jul 2008
MARCAINE E 0.25% LIQ PRT (9.1 MCG)	02018322	Cancelled Post Market	Sanofi Canada, Inc.	Aug 2001
MARCAINE E LIQ PRT 0.50% (9.1 MCG)	02018330	Cancelled Post Market	Sanofi Canada, Inc.	Aug 2001

Notices of Compliance

Approvals of drug submissions that list it, newest first.

TRI-SOLFENSeptember 22, 2026 · NOC 38329
ARTICAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE INJECTIONJune 24, 2026 · NOC 37765
ARTICAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION - N; ARTICAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION - SPOctober 14, 2025 · NOC 36160
SEPTANEST N; SEPTANEST SPJanuary 29, 2025 · NOC 34755
VIVACAINEJanuary 23, 2025 · NOC 34742
MARCAINE EDecember 12, 2024 · NOC 34544
SENSORCAINE; SENSORCAINE WITH EPINEPHRINENovember 29, 2023 · NOC 32199
MARCAINE EMay 11, 2023 · NOC 30711
ORABLOC 1:100,000; ORABLOC 1:200,000February 9, 2023 · NOC 30105
ARTICAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE INJECTIONJanuary 25, 2023 · NOC 29978
TRI-SOLFENJune 21, 2022 · NOC 28425
MARCAINE EMay 2, 2022 · NOC 28070
SEPTANEST N; SEPTANEST SPNovember 16, 2021 · NOC 27042
4% ASTRACAINE DENTAL WITH EPINEPHRINE 1:200,000; 4% ASTRACAINE DENTAL WITH EPINEPHRINE FORTE 1:100,000June 15, 2018 · NOC 20988
ARTICAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE INJECTIONApril 17, 2018 · NOC 20759
ZORCAINEMarch 26, 2018 · NOC 20663
MARCAINEMarch 26, 2018 · NOC 20664
ORABLOC 1:100,000; ORABLOC 1:200,000January 11, 2018 · NOC 20294
MARCAINE ESeptember 7, 2017 · NOC 19773
SENSORCAINE; SENSORCAINE WITH EPINEPHRINEAugust 15, 2017 · NOC 19656
VIVACAINEJune 21, 2017 · NOC 19452
4% ASTRACAINE DENTAL WITH EPINEPHRINE 1:200,000; 4% ASTRACAINE DENTAL WITH EPINEPHRINE FORTE 1:100,000January 12, 2015 · NOC 16514
BUPIVACAINE HCL 0.5% AND EPINEPHRINE 1:200,000 INJECTIONApril 16, 2012 · NOC 13206
POSICAINE SP; POSICAINE NMarch 30, 2012 · NOC 13164
ORABLOC 1:100,000; ORABLOC 1:200,000February 11, 2011 · NOC 12066
DENTSPLY 4% PRILOCAINE AND EPINEPHRINE INJECTION 1:200,000March 16, 2010 · NOC 11151
KARTICAINE; KARTICAINE FORTEDecember 21, 2009 · NOC 10876
MARCAINEJune 16, 2008 · NOC 9626
VIVACAINE (BUPIVACAINE HCL 0.5% & EPINEPHRINE 1:200,000 INJ, USP)February 12, 2008 · NOC 9370
ZORCAINEMay 1, 2007 · NOC 8934
SENSORCAINE FORTEApril 15, 2005 · NOC 6434
ZORCAINENovember 17, 2004 · NOC 5913
4% CITANEST FORTE DENTAL WITH EPINEPHRINE 1:200,000May 14, 2004 · NOC 2868
MARCAINE EMay 4, 2004 · NOC 2185
4% ASTRACAINE DENTAL (WITH EPINEPHRINE 1:100,000); 4% ASTRACAINE DENTAL (WITH EPINEPHRINE 1:200,000)December 2, 2003 · NOC 265
SENSORCAINE; SENSORCAINE WITH EPINEPHRINE; SENSORCAINE SPINAL; SENSORCAINE FORTEJuly 15, 2003 · NOC 222
MARCAINE EMarch 24, 2000 · NOC 1001
SENSORCAINE FORTEMarch 24, 2000 · NOC 1003
SENSORCAINE WITH EPINEPHRINEMarch 24, 2000 · NOC 1006
SEPTANEST SP; SEPTANEST NAugust 9, 1994 · NOC 5166